3H7R

Crystal structure of the plant stress-response enzyme AKR4C8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Aldo-keto reductase	polymer	331	36901.2	1	UniProt (O80944) Pfam (PF00248) In PDB	Arabidopsis thaliana (Mouse-ear cress)	Putative alcohol dehydrogenase, Protein At2g37760.2
2	A	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	1	Chemie (NAP)
3	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
4	A	1,2-ETHANEDIOL	non-polymer		62.1	12	Chemie (EDO)
5		water	water		18.0	406	Chemie (HOH)

Sequence modifications

A: 1 - 311 (UniProt: O80944)

PDB	External Database	Details
Met -19	-	insertion
Gly -18	-	insertion
Ser -17	-	insertion
Ser -16	-	insertion
His -15	-	insertion
His -14	-	insertion
His -13	-	insertion
His -12	-	insertion
His -11	-	insertion
His -10	-	insertion
Ser -9	-	insertion
Ser -8	-	insertion
Gly -7	-	insertion
Leu -6	-	insertion
Val -5	-	insertion
Pro -4	-	insertion
Arg -3	-	insertion
Gly -2	-	insertion
Ser -1	-	insertion
His 0	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36901.2
Non-Polymers*	Number of molecules	14
	Total formula weight	1547.3
All*	Total formula weight	38448.5

*Water molecules are not included.