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3GPC

Crystal structure of human Acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a complex with CoA

Replaces:  3EYN
Summary for 3GPC
Entry DOI10.2210/pdb3gpc/pdb
Related3B7W 3C5E 3DAY 3EQ6
DescriptorAcyl-coenzyme A synthetase ACSM2A, MAGNESIUM ION, COENZYME A, ... (4 entities in total)
Functional Keywordsmiddle-chain acyl-coa synthetase, xenobiotic/medium-chain fatty acid-coa ligase, atp-binding, fatty acid metabolism, lipid metabolism, magnesium, metal-binding, mitochondrion, nucleotide-binding polymorphism, transit peptide, ligase, nucleotide-binding
Biological sourceHomo sapiens (Human)
Cellular locationMitochondrion matrix : Q08AH3
Total number of polymer chains2
Total formula weight128252.80
Authors
Primary citationKochan, G.,Pilka, E.S.,von Delft, F.,Oppermann, U.,Yue, W.W.
Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A
J.Mol.Biol., 388:997-1008, 2009
Cited by
PubMed: 19345228
DOI: 10.1016/j.jmb.2009.03.064
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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数据于2024-09-18公开中

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