3GDL
Crystal structure of the orotidine 5'-monophosphate decarboxylase from Saccharomyces cerevisiae complexed with 6-azauridine 5'-monophosphate
Summary for 3GDL
Entry DOI | 10.2210/pdb3gdl/pdb |
Related | 1DQW 3GDK 3GDM 3GDR 3GDT |
Descriptor | Orotidine 5'-phosphate decarboxylase, 6-AZA URIDINE 5'-MONOPHOSPHATE (3 entities in total) |
Functional Keywords | orotidine 5'-monophosphate decarboxylase, saccharomyces cerevisiae, 6-azauridine 5'-monophosphate, decarboxylase, lyase, phosphoprotein, pyrimidine biosynthesis, ubl conjugation |
Biological source | Saccharomyces cerevisiae (yeast) |
Total number of polymer chains | 2 |
Total formula weight | 59209.40 |
Authors | Fedorov, A.A.,Fedorov, E.V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C. (deposition date: 2009-02-24, release date: 2009-06-23, Last modification date: 2023-09-06) |
Primary citation | Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry, 48:5518-5531, 2009 Cited by PubMed: 19435314DOI: 10.1021/bi900623r PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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