Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| A | 0006222 | biological_process | UMP biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| B | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| B | 0006222 | biological_process | UMP biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE UP6 A 301 |
| Chain | Residue |
| A | SER35 |
| A | GLN215 |
| A | TYR217 |
| A | GLY234 |
| A | ARG235 |
| A | HOH274 |
| A | HOH278 |
| A | HOH283 |
| A | HOH306 |
| A | HOH358 |
| B | ASP96 |
| A | ASP37 |
| B | ILE97 |
| B | THR100 |
| A | LYS59 |
| A | HIS61 |
| A | ASP91 |
| A | LYS93 |
| A | LEU153 |
| A | SER154 |
| A | PRO202 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE UP6 B 301 |
| Chain | Residue |
| A | ASP96 |
| A | ILE97 |
| A | THR100 |
| B | SER35 |
| B | ASP37 |
| B | LYS59 |
| B | HIS61 |
| B | ASP91 |
| B | LYS93 |
| B | LEU153 |
| B | SER154 |
| B | PRO202 |
| B | GLN215 |
| B | TYR217 |
| B | GLY234 |
| B | ARG235 |
| B | HOH282 |
| B | HOH287 |
| B | HOH294 |
| B | HOH314 |
| B | HOH387 |
Functional Information from PROSITE/UniProt
| site_id | PS00156 |
| Number of Residues | 14 |
| Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. LFeDrKfaDIGnTV |
| Chain | Residue | Details |
| A | LEU88-VAL101 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor |
| Chain | Residue | Details |
| A | LYS93 | |
| B | LYS93 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP37 | |
| B | ARG235 | |
| A | LYS59 | |
| A | ASP91 | |
| A | TYR217 | |
| A | ARG235 | |
| B | ASP37 | |
| B | LYS59 | |
| B | ASP91 | |
| B | TYR217 | |
| Chain | Residue | Details |
| A | SER2 | |
| B | SER2 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:12872131 |
| Chain | Residue | Details |
| A | LYS93 | |
| A | LYS209 | |
| A | LYS253 | |
| B | LYS93 | |
| B | LYS209 | |
| B | LYS253 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dbt |
| Chain | Residue | Details |
| A | ASP91 | |
| A | LYS93 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dbt |
| Chain | Residue | Details |
| B | ASP91 | |
| B | LYS93 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1dbt |
| Chain | Residue | Details |
| A | LYS59 | |
| A | ASP96 | |
| A | ASP91 | |
| A | LYS93 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1dbt |
| Chain | Residue | Details |
| B | LYS59 | |
| B | ASP96 | |
| B | ASP91 | |
| B | LYS93 | |
