3G5U
Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Summary for 3G5U
Entry DOI | 10.2210/pdb3g5u/pdb |
Related | 3G60 3G61 |
Descriptor | Multidrug resistance protein 1a, MERCURY (II) ION (2 entities in total) |
Functional Keywords | p-glycoprotein, multidrug resistance, pgp, cyclic peptide, membrane protein |
Biological source | Mus musculus (mouse) |
Total number of polymer chains | 2 |
Total formula weight | 286138.77 |
Authors | Aller, S.G.,Yu, J.,Ward, A.,Weng, Y.,Chittaboina, S.,Zhuo, R.,Harrell, P.M.,Trinh, Y.T.,Zhang, Q.,Urbatsch, I.L.,Chang, G. (deposition date: 2009-02-05, release date: 2009-03-24, Last modification date: 2024-02-21) |
Primary citation | Aller, S.G.,Yu, J.,Ward, A.,Weng, Y.,Chittaboina, S.,Zhuo, R.,Harrell, P.M.,Trinh, Y.T.,Zhang, Q.,Urbatsch, I.L.,Chang, G. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science, 323:1718-1722, 2009 Cited by PubMed: 19325113DOI: 10.1126/science.1168750 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.8 Å) |
Structure validation
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