3FEX
Crystal structure of the CBC-importin alpha complex.
Summary for 3FEX
Entry DOI | 10.2210/pdb3fex/pdb |
Related | 3FEX 3FEY |
Descriptor | Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, Importin subunit alpha-2 (3 entities in total) |
Functional Keywords | cap binding complex, importin alpha, nuclear transport, coiled coil, mrna transport, nucleus, phosphoprotein, rna-binding, acetylation, cytoplasm, host-virus interaction, translation, protein transport |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q09161 P52298 Cytoplasm: P52292 |
Total number of polymer chains | 3 |
Total formula weight | 160767.96 |
Authors | Dias, S.M.G.,Ambrosio, A.L.B.,Cerione, R.A. (deposition date: 2008-12-01, release date: 2009-08-11, Last modification date: 2023-09-06) |
Primary citation | Dias, S.M.,Wilson, K.F.,Rojas, K.S.,Ambrosio, A.L.,Cerione, R.A. The molecular basis for the regulation of the cap-binding complex by the importins. Nat.Struct.Mol.Biol., 16:930-937, 2009 Cited by PubMed: 19668212DOI: 10.1038/nsmb.1649 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.549 Å) |
Structure validation
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