3F71
Crystal structure of E18D DJ-1 with oxidized C106
Summary for 3F71
| Entry DOI | 10.2210/pdb3f71/pdb |
| Related | 1p5f 1soa 3ezg |
| Descriptor | Protein DJ-1 (2 entities in total) |
| Functional Keywords | cysteine oxidation, parkinson disease, chaperone, cytoplasm, disease mutation, nucleus, oncogene, oxidation, phosphoprotein, polymorphism, ubl conjugation |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q99497 |
| Total number of polymer chains | 1 |
| Total formula weight | 20852.03 |
| Authors | Lakshminarasimhan, M.,Wilson, M.A. (deposition date: 2008-11-07, release date: 2008-12-30, Last modification date: 2023-11-15) |
| Primary citation | Blackinton, J.,Lakshminarasimhan, M.,Thomas, K.J.,Ahmad, R.,Greggio, E.,Raza, A.S.,Cookson, M.R.,Wilson, M.A. Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1. J.Biol.Chem., 284:6476-6485, 2009 Cited by PubMed: 19124468DOI: 10.1074/jbc.M806599200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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