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3EZG

Crystal structure of E18Q DJ-1 with oxidized C106

Summary for 3EZG
Entry DOI10.2210/pdb3ezg/pdb
Related1SOA 3CY6
DescriptorProtein DJ-1 (2 entities in total)
Functional Keywordscysteine oxidation, sulfinic acid, chaperone, disease mutation, nucleus, oncogene, oxidation, parkinson disease, phosphoprotein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor: Q99497
Total number of polymer chains1
Total formula weight20881.07
Authors
Lakshminarasimhan, M.,Wilson, M.A. (deposition date: 2008-10-22, release date: 2008-12-30, Last modification date: 2023-09-06)
Primary citationBlackinton, J.,Lakshminarasimhan, M.,Thomas, K.J.,Ahmad, R.,Greggio, E.,Raza, A.S.,Cookson, M.R.,Wilson, M.A.
Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1.
J.Biol.Chem., 284:6476-6485, 2009
Cited by
PubMed: 19124468
DOI: 10.1074/jbc.M806599200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.15 Å)
Structure validation

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