1SOA

Human DJ-1 with sulfinic acid

Summary for 1SOA

• Entry DOI: 10.2210/pdb1soa/pdb
• Related: 1p5f
• Descriptor: RNA-binding protein regulatory subunit; oncogene DJ1 (2 entities in total)
• Functional Keywords: parkinson's disease, dj-1/thij/pfpi familiy, protein binding
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane ; Lipid-anchor : Q99497
• Total number of polymer chains: 1
• Total formula weight: 19949.05

Authors

Canet-Aviles, R.,Wilson, M.A.,Miller, D.W.,Ahmad, R.,McLendon, C.,Bandyopadhyay, S.,Baptista, M.J.,Ringe, D.,Petsko, G.A.,Cookson, M.R. (deposition date: 2004-03-13, release date: 2004-06-22, Last modification date: 2023-08-23)

• Primary citation: Wilson, M.A.,Miller, D.W.,Ahmad, R.,McLendon, C.,Bandyopadhyay, S.,Baptista, M.J.,Ringe, D.,Petsko, G.A.,Cookson, M.R.; The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization.; Proc.Natl.Acad.Sci.USA, 101:9103-9108, 2004; PubMed: 15181200; DOI: 10.1073/pnas.0308089100

Experimental method

X-RAY DIFFRACTION (1.2 Å)