3EQL

Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic myxopyronin

3EQL の概要

• エントリーDOI: 10.2210/pdb3eql/pdb
• 関連するPDBエントリー: 1IW7 1SMY 2A68 2A69 2A6E 2A6H 2BE5
• 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (9 entities in total)
• 機能のキーワード: rna polymerase holoenzyme, myxopyronin, antibiotic, transcription regulation, dna-directed rna polymerase, nucleotidyltransferase, transcription, transferase, dna-binding, sigma factor
• 由来する生物種: Thermus thermophilus; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 854440.40

構造登録者

Vassylyev, D.G.,Vassylyeva, M.N.,Artsimovitch, I. (登録日: 2008-09-30, 公開日: 2008-10-28, 最終更新日: 2023-09-06)

• 主引用文献: Belogurov, G.A.,Vassylyeva, M.N.,Sevostyanova, A.,Appleman, J.R.,Xiang, A.X.,Lira, R.,Webber, S.E.,Klyuyev, S.,Nudler, E.,Artsimovitch, I.,Vassylyev, D.G.; Transcription inactivation through local refolding of the RNA polymerase structure.; Nature, 457:332-335, 2009; PubMed: 18946472; DOI: 10.1038/nature07510

実験手法

X-RAY DIFFRACTION (2.7 Å)