3ECR
Structure of human porphobilinogen deaminase
Summary for 3ECR
Entry DOI | 10.2210/pdb3ecr/pdb |
Descriptor | Porphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid (3 entities in total) |
Functional Keywords | human porphobilinogen deaminase, heme biosynthesis, porphobilinogen hinge, alternative splicing, cytoplasm, disease mutation, porphyrin biosynthesis, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm (Probable): P08397 |
Total number of polymer chains | 2 |
Total formula weight | 80151.37 |
Authors | |
Primary citation | Song, G.,Li, Y.,Cheng, C.,Zhao, Y.,Gao, A.,Zhang, R.,Joachimiak, A.,Shaw, N.,Liu, Z.J. Structural insight into acute intermittent porphyria. Faseb J., 23:396-404, 2009 Cited by PubMed: 18936296DOI: 10.1096/fj.08-115469 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.182 Å) |
Structure validation
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