3E0Q
Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor
Summary for 3E0Q
| Entry DOI | 10.2210/pdb3e0q/pdb |
| Related | 1TCU 1TCV 1TD1 |
| Descriptor | Purine-nucleoside phosphorylase, DIMETHYL SULFOXIDE, 6-amino-5-bromo-1,2,3,4-tetrahydropyrimidine-2,4-dione, ... (4 entities in total) |
| Functional Keywords | monocyclic inhibitor, glycosyltransferase, transferase |
| Biological source | Schistosoma mansoni (Blood fluke) |
| Total number of polymer chains | 3 |
| Total formula weight | 94522.29 |
| Authors | Pereira, H.M.,Berdini, V.,Ferri, M.R.,Cleasby, A.,Garratt, R.C. (deposition date: 2008-07-31, release date: 2009-08-18, Last modification date: 2023-08-30) |
| Primary citation | Pereira, H.M.,Berdini, V.,Ferri, M.R.,Cleasby, A.,Garratt, R.C. Crystal structure of Schistosoma purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor. Acta Trop., 114:97-102, 2010 Cited by PubMed: 20122887DOI: 10.1016/j.actatropica.2010.01.010 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report
