3E0Q
Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Purine-nucleoside phosphorylase | polymer | 287 | 31197.3 | 3 | UniProt (Q9BMI9) | Schistosoma mansoni (Blood fluke) | |
| 2 | D, E, G, I (A, B, C) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 3 | F, H, J (A, B, C) | 6-amino-5-bromo-1,2,3,4-tetrahydropyrimidine-2,4-dione | non-polymer | 206.0 | 3 | Chemie (JFD) | |||
| 4 | K, L, M (A, B, C) | water | water | 18.0 | 584 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 93591.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 930.5 | |
| All* | Total formula weight | 94522.3 |
