Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex

Summary for 3DVA

Related1W85 1W88 3DUF 3DV0
DescriptorPyruvate dehydrogenase E1 component subunit alpha, Pyruvate dehydrogenase E1 component subunit beta, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, ... (7 entities in total)
Functional Keywordsoxidoreductase, pyruvate, dehydrogenase, dihydrolipoyl, acetyl transferase, multienzyme complex, transferase, glycolysis, phosphoprotein, thiamine pyrophosphate, acyltransferase, oxidoreductase-transferase complex, oxidoreductase/transferase
Biological sourceBacillus stearothermophilus
Total number of polymer chains10
Total molecular weight402588.64
Pei, X.Y.,Titman, C.M.,Frank, R.A.W.,Leeper, F.J.,Luisi, B.F. (deposition date: 2008-07-18, release date: 2009-01-13, Last modification date: 2011-07-13)
Primary citation
Pei, X.Y.,Titman, C.M.,Frank, R.A.,Leeper, F.J.,Luisi, B.F.
Snapshots of catalysis in the e1 subunit of the pyruvate dehydrogenase multienzyme complex
Structure, 16:1860-1872, 2008
PubMed: 19081062 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2008.10.009
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.246100.4%1.8%1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report