3DOX
X-ray structure of HIV-1 protease in situ product complex
Summary for 3DOX
Entry DOI | 10.2210/pdb3dox/pdb |
Related | 1G6L 1LV1 2NPH |
Descriptor | HIV-1 PROTEASE, A PEPTIDE SUBSTRATE-SQNY, A PEPTIDE SUBSTRATE-PIV, ... (4 entities in total) |
Functional Keywords | hiv-1 protease; transition state; reaction intermediate; catalysis; inhibitor; x-ray crystallography, aids, aspartyl protease, capsid maturation, capsid protein, cytoplasm, dna integration, dna recombination, dna-directed dna polymerase, endonuclease, host-virus interaction, hydrolase, lipoprotein, magnesium, metal-binding, multifunctional enzyme, myristate, nuclease, nucleotidyltransferase, nucleus, phosphoprotein, protease, ribosomal frameshifting, rna-binding, rna-directed dna polymerase, transferase, viral nucleoprotein, virion, zinc, zinc-finger |
Biological source | Human immunodeficiency virus type 1 (isolate HXB2 group M subtype B) (HIV-1, HIV-1 M:B_HXB2R) More |
Cellular location | Gag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P04585 |
Total number of polymer chains | 3 |
Total formula weight | 22740.68 |
Authors | Hosur, M.V.,Ferrer, J.-L.,Das, A.,Prashar, V.,Bihani, S. (deposition date: 2008-07-07, release date: 2008-09-09, Last modification date: 2024-05-29) |
Primary citation | Bihani, S.,Das, A.,Prashar, V.,Ferrer, J.-L.,Hosur, M.V. X-ray structure of HIV-1 protease in situ product complex Proteins, 74:594-602, 2009 Cited by PubMed: 18704947DOI: 10.1002/prot.22174 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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