3CO6
Crystal Structure of FoxO1 DBD Bound to DBE1 DNA
Summary for 3CO6
Entry DOI | 10.2210/pdb3co6/pdb |
Related | 3CO7 3COA |
Descriptor | DNA (5'-D(*DTP*DGP*DGP*DTP*DTP*DTP*DGP*DTP*DTP*DTP*DAP*DCP*DCP*DTP*DTP*DG)-3'), DNA (5'-D(*DCP*DAP*DAP*DGP*DGP*DTP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3'), Forkhead box protein O1, ... (6 entities in total) |
Functional Keywords | winged helix, forkhead domain, chromosomal rearrangement, cytoplasm, dna-binding, nucleus, phosphoprotein, proto-oncogene, transcription, transcription regulation, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : Q12778 |
Total number of polymer chains | 3 |
Total formula weight | 21100.50 |
Authors | Brent, M.M.,Anand, R.,Marmorstein, R. (deposition date: 2008-03-27, release date: 2008-09-16, Last modification date: 2024-02-21) |
Primary citation | Brent, M.M.,Anand, R.,Marmorstein, R. Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification. Structure, 16:1407-1416, 2008 Cited by PubMed: 18786403DOI: 10.1016/j.str.2008.06.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report