3CO6
Crystal Structure of FoxO1 DBD Bound to DBE1 DNA
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 13 |
| Chain | Residue |
| A | HOH39 |
| A | HOH40 |
| A | HOH41 |
| B | HOH55 |
| B | HOH56 |
| B | HOH57 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA C 2 |
| Chain | Residue |
| C | PHE223 |
| C | HOH264 |
| C | LEU217 |
| C | SER218 |
| C | HIS220 |
Functional Information from PROSITE/UniProt
| site_id | PS00658 |
| Number of Residues | 7 |
| Details | FORK_HEAD_2 Fork head domain signature 2. WKNSIRH |
| Chain | Residue | Details |
| C | TRP209-HIS215 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 76 |
| Details | DNA binding: {"description":"Fork-head","evidences":[{"source":"PROSITE-ProRule","id":"PRU00089","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Region: {"description":"DNA-binding","evidences":[{"source":"PubMed","id":"18786403","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Site: {"description":"DNA-binding","evidences":[{"source":"PubMed","id":"18786403","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by STK4/MST1","evidences":[{"source":"PubMed","id":"18786403","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19221179","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21245099","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphoserine; by STK4/MST1","evidences":[{"source":"PubMed","id":"18786403","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
