3CF5

Thiopeptide antibiotic Thiostrepton bound to the large ribosomal subunit of Deinococcus radiodurans

3CF5 の概要

• エントリーDOI: 10.2210/pdb3cf5/pdb
• 関連するPDBエントリー: 1D8T 1E9W 1OLN 2C77 2JQ7 2ZJP
• 関連するBIRD辞書のPRD_ID: PRD_000223
• 分子名称: 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L6, 50S RIBOSOMAL PROTEIN L11, ... (32 entities in total)
• 機能のキーワード: ribosome-antibiotic complex, antibiotic, ribosome, thiostrepton, rna, l11, thiopeptide, thiazole, thiazoline, pyridine, translation inhibition, ribosome/antibiotic
• 由来する生物種: DEINOCOCCUS RADIODURANS; 詳細
• タンパク質・核酸の鎖数: 31
• 化学式量合計: 1367119.57

構造登録者

Harms, J.M.,Wilson, D.N.,Schluenzen, F.,Connell, S.R.,Stachelhaus, T.,Zaborowska, Z.,Spahn, C.M.T.,Fucini, P. (登録日: 2008-03-02, 公開日: 2008-06-17, 最終更新日: 2023-11-15)

• 主引用文献: Harms, J.M.,Wilson, D.N.,Schluenzen, F.,Connell, S.R.,Stachelhaus, T.,Zaborowska, Z.,Spahn, C.M.,Fucini, P.; Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.; Mol.Cell, 30:26-, 2008; PubMed: 18406324; DOI: 10.1016/J.MOLCEL.2008.01.009

実験手法

X-RAY DIFFRACTION (3.3 Å)