3BFU
Structure of the ligand-binding core of GluR2 in complex with the agonist (R)-TDPA at 1.95 A resolution
Summary for 3BFU
Entry DOI | 10.2210/pdb3bfu/pdb |
Related | 1FTM 3BFT |
Descriptor | Glutamate receptor 2, (2R)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propanoic acid (3 entities in total) |
Functional Keywords | ampa receptor, glur2, ligand-binding core, agonist, (r)-tdpa, alternative splicing, cell junction, endoplasmic reticulum, glycoprotein, ion transport, ionic channel, lipoprotein, membrane, palmitate, phosphoprotein, postsynaptic cell membrane, rna editing, synapse, transmembrane, transport, membrane protein |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 4 |
Total formula weight | 117643.50 |
Authors | Beich-Frandsen, M.,Mirza, O.,Vestergaard, B.,Gajhede, M.,Kastrup, J.S. (deposition date: 2007-11-23, release date: 2008-10-14, Last modification date: 2023-11-01) |
Primary citation | Beich-Frandsen, M.,Pickering, D.S.,Mirza, O.,Johansen, T.N.,Greenwood, J.,Vestergaard, B.,Schousboe, A.,Gajhede, M.,Liljefors, T.,Kastrup, J.S. Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. J.Med.Chem., 51:1459-1463, 2008 Cited by PubMed: 18269227DOI: 10.1021/jm701126w PDB entries with the same primary citation |
Experimental method |
Structure validation
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