3BFU

Structure of the ligand-binding core of GluR2 in complex with the agonist (R)-TDPA at 1.95 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Glutamate receptor 2	polymer	263	29221.7	4	UniProt (P19491) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Rat)	GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2
2	E, F, G, H (A, B, C, D)	(2R)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propanoic acid	non-polymer		189.2	4	Chemie (R2P)
3	I, J, K, L (A, B, C, D)	water	water		18.0	1218	Chemie (HOH)

Sequence modifications

A, B, C, D: 3 - 117 (UniProt: P19491)

PDB	External Database	Details
Gly 1	-	expression tag
Ala 2	-	expression tag

A, B, C, D: 120 - 263 (UniProt: P19491)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	116886.7
Non-Polymers*	Number of molecules	4
	Total formula weight	756.8
All*	Total formula weight	117643.5

*Water molecules are not included.