3B7L
Human farnesyl diphosphate synthase complexed with MG and minodronate
Summary for 3B7L
Entry DOI | 10.2210/pdb3b7l/pdb |
Related | 1YQ7 1YV5 1ZW5 2QIS |
Descriptor | Farnesyl pyrophosphate synthetase, MAGNESIUM ION, (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), ... (4 entities in total) |
Functional Keywords | isoprenoid pathway, cholesterol synthesis, bisphosphonate, structural genomics, structural genomics consortium, sgc, cholesterol biosynthesis, host-virus interaction, isoprene biosynthesis, lipid synthesis, steroid biosynthesis, sterol biosynthesis, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P14324 |
Total number of polymer chains | 1 |
Total formula weight | 41321.01 |
Authors | Pilka, E.S.,Dunford, J.E.,Guo, K.,Pike, A.C.W.,Kavanagh, K.L.,von Delft, F.,Ebetino, F.H.,Arrowsmith, C.H.,Edwards, A.M.,Russell, R.G.G.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2007-10-31, release date: 2007-11-13, Last modification date: 2023-08-30) |
Primary citation | Pilka, E.S.,Dunford, J.E.,Guo, K.,Pike, A.C.W.,Kavanagh, K.L.,von Delft, F.,Ebetino, F.H.,Arrowsmith, C.H.,Edwards, A.M.,Russell, R.G.G.,Oppermann, U. Human farnesyl diphosphate synthase complexed with MG and minodronate. TO BE PUBLISHED, |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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