3B7L
Human farnesyl diphosphate synthase complexed with MG and minodronate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Farnesyl pyrophosphate synthetase | polymer | 356 | 40901.6 | 1 | UniProt (P14324) Pfam (PF00348) | Homo sapiens (human) | FPP synthetase, FPS, Farnesyl diphosphate synthetase [Includes: Dimethylallyltranstransferase (EC 2.5.1.1) and Geranyltranstransferase (EC 2.5.1.10)] |
| 2 | B, C, D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | F (A) | (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID) | non-polymer | 322.1 | 1 | Chemie (M0N) | |||
| 4 | G (A) | water | water | 18.0 | 268 | Chemie (HOH) |
Sequence modifications
A: 1 - 353 (UniProt: P14324)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40901.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 419.4 | |
| All* | Total formula weight | 41321.0 |
