1YQ7

Human farnesyl diphosphate synthase complexed with risedronate

Summary for 1YQ7

• Entry DOI: 10.2210/pdb1yq7/pdb
• Descriptor: Farnesyl pyrophosphate synthetase, MAGNESIUM ION, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: isoprenoid pathway, cholesterol biosynthesis, bisphosphonate inhibitor, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P14324
• Total number of polymer chains: 1
• Total formula weight: 43559.75

Authors

Kavanagh, K.L.,Guo, K.,Von delft, F.,Arrowsmith, C.,Sundstrom, M.,Edwards, A.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2005-02-01, release date: 2005-02-22, Last modification date: 2023-10-25)

• Primary citation: Kavanagh, K.L.,Guo, K.,Oppermann, U.; Human farnesyl diphosphate complexed with clinical inhibitor risedronate; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)