2QIS

Crystal structure of human farnesyl pyrophosphate synthase T210S mutant bound to risedronate

Summary for 2QIS

• Entry DOI: 10.2210/pdb2qis/pdb
• Related: 1yv5 1zw5
• Descriptor: Farnesyl pyrophosphate synthetase, MAGNESIUM ION, 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, ... (4 entities in total)
• Functional Keywords: trans-prenyltransferase, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P14324
• Total number of polymer chains: 1
• Total formula weight: 43355.79

Authors

Kavanagh, K.L.,Dunford, J.E.,Hozjan, V.,Evdokimov, A.,Gileadi, O.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Sundstrom, M.,Edwards, A.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2007-07-05, release date: 2007-07-24, Last modification date: 2023-08-30)

• Primary citation: Kavanagh, K.L.,Dunford, J.E.,Hozjan, V.,Evdokimov, A.,Gileadi, O.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Sundstrom, M.,Edwards, A.,Oppermann, U.; Crystal structure of human farnesyl pyrophosphate synthase T210S mutant bound to risedronate.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)