3B7L

Human farnesyl diphosphate synthase complexed with MG and minodronate

3B7L の概要

• エントリーDOI: 10.2210/pdb3b7l/pdb
• 関連するPDBエントリー: 1YQ7 1YV5 1ZW5 2QIS
• 分子名称: Farnesyl pyrophosphate synthetase, MAGNESIUM ION, (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), ... (4 entities in total)
• 機能のキーワード: isoprenoid pathway, cholesterol synthesis, bisphosphonate, structural genomics, structural genomics consortium, sgc, cholesterol biosynthesis, host-virus interaction, isoprene biosynthesis, lipid synthesis, steroid biosynthesis, sterol biosynthesis, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P14324
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41321.01

構造登録者

Pilka, E.S.,Dunford, J.E.,Guo, K.,Pike, A.C.W.,Kavanagh, K.L.,von Delft, F.,Ebetino, F.H.,Arrowsmith, C.H.,Edwards, A.M.,Russell, R.G.G.,Oppermann, U.,Structural Genomics Consortium (SGC) (登録日: 2007-10-31, 公開日: 2007-11-13, 最終更新日: 2023-08-30)

• 主引用文献: Pilka, E.S.,Dunford, J.E.,Guo, K.,Pike, A.C.W.,Kavanagh, K.L.,von Delft, F.,Ebetino, F.H.,Arrowsmith, C.H.,Edwards, A.M.,Russell, R.G.G.,Oppermann, U.; Human farnesyl diphosphate synthase complexed with MG and minodronate.; TO BE PUBLISHED,

実験手法

X-RAY DIFFRACTION (1.95 Å)