3B2Z

Crystal Structure of ADAMTS4 (apo form)

Summary for 3B2Z

DescriptorADAMTS-4, ZINC ION, CALCIUM ION, ... (4 entities in total)
Functional Keywordsmetalloprotease, aggrecanase, cleavage on pair of basic residues, extracellular matrix, glycoprotein, hydrolase, metal-binding, secreted, zymogen
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space, extracellular matrix (By similarity) O75173
Total number of polymer chains8
Total molecular weight274937.8
Authors
Mosyak, L.,Stahl, M.,Somers, W. (deposition date: 2007-10-19, release date: 2007-12-25, Last modification date: 2011-07-13)
Primary citation
Mosyak, L.,Georgiadis, K.,Shane, T.,Svenson, K.,Hebert, T.,McDonagh, T.,Mackie, S.,Olland, S.,Lin, L.,Zhong, X.,Kriz, R.,Reifenberg, E.L.,Collins-Racie, L.A.,Corcoran, C.,Freeman, B.,Zollner, R.,Marvell, T.,Vera, M.,Sum, P.E.,Lavallie, E.R.,Stahl, M.,Somers, W.
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
Protein Sci., 17:16-21, 2008
PubMed: 18042673 (PDB entries with the same primary citation)
DOI: 10.1110/ps.073287008
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers120.5%3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3b2z
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Molmil generated image of 3b2z
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Molmil generated image of 3b2z
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More Biological unit images

Molmil generated image of 3b2z
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Molmil generated image of 3b2z
rotated about x axis by 90°
Molmil generated image of 3b2z
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3b2z.pdb1.gz [51.44 KB])
Coordinate files for Biological unit (3b2z.pdb4.gz [51.01 KB])
Coordinate files for Biological unit (3b2z.pdb5.gz [49.72 KB])
Coordinate files for Biological unit (3b2z.pdb8.gz [49.52 KB])
Coordinate files for Biological unit (3b2z.pdb3.gz [50.76 KB])
Coordinate files for Biological unit (3b2z.pdb7.gz [50.61 KB])
Coordinate files for Biological unit (3b2z.pdb6.gz [50.76 KB])
Coordinate files for Biological unit (3b2z.pdb2.gz [50.5 KB])