3B2Z
Crystal Structure of ADAMTS4 (apo form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | ADAMTS-4 | polymer | 316 | 34221.7 | 8 | UniProt (O75173) Pfam (PF01421) Pfam (PF17771) | Homo sapiens (human) | A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS 4, ADAM-TS4, Aggrecanase-1, ADMP-1 |
| 2 | AA, DA, I, L, O... (G, H, A, B, C...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | BA, CA, EA, FA, J... (G, H, A, B, C...) | CALCIUM ION | non-polymer | 40.1 | 16 | Chemie (CA) | |||
| 4 | GA, HA, IA, JA, KA... (A, B, C, D, E...) | water | water | 18.0 | 299 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 213 - 520 (UniProt: O75173)
| PDB | External Database | Details |
|---|---|---|
| Gln 362 | Glu 362 | engineered mutation |
| Asp 521 | - | expression tag |
| Tyr 522 | - | expression tag |
| Lys 523 | - | expression tag |
| Asp 524 | - | expression tag |
| Asp 525 | - | expression tag |
| Asp 526 | - | expression tag |
| Asp 527 | - | expression tag |
| Lys 528 | - | expression tag |
| Gln 362 | Glu 362 | engineered mutation |
| Asp 521 | - | expression tag |
| Tyr 522 | - | expression tag |
| Lys 523 | - | expression tag |
| Asp 524 | - | expression tag |
| Asp 525 | - | expression tag |
| Asp 526 | - | expression tag |
| Asp 527 | - | expression tag |
| Lys 528 | - | expression tag |
| Gln 362 | Glu 362 | engineered mutation |
| Asp 521 | - | expression tag |
| Tyr 522 | - | expression tag |
| Lys 523 | - | expression tag |
| Asp 524 | - | expression tag |
| Asp 525 | - | expression tag |
| Asp 526 | - | expression tag |
| Asp 527 | - | expression tag |
| Lys 528 | - | expression tag |
| Gln 362 | Glu 362 | engineered mutation |
| Asp 521 | - | expression tag |
| Tyr 522 | - | expression tag |
| Lys 523 | - | expression tag |
| Asp 524 | - | expression tag |
| Asp 525 | - | expression tag |
| Asp 526 | - | expression tag |
| Asp 527 | - | expression tag |
| Lys 528 | - | expression tag |
| Gln 362 | Glu 362 | engineered mutation |
| Asp 521 | - | expression tag |
| Tyr 522 | - | expression tag |
| Lys 523 | - | expression tag |
| Asp 524 | - | expression tag |
| Asp 525 | - | expression tag |
| Asp 526 | - | expression tag |
| Asp 527 | - | expression tag |
| Lys 528 | - | expression tag |
| Gln 362 | Glu 362 | engineered mutation |
| Asp 521 | - | expression tag |
| Tyr 522 | - | expression tag |
| Lys 523 | - | expression tag |
| Asp 524 | - | expression tag |
| Asp 525 | - | expression tag |
| Asp 526 | - | expression tag |
| Asp 527 | - | expression tag |
| Lys 528 | - | expression tag |
| Gln 362 | Glu 362 | engineered mutation |
| Asp 521 | - | expression tag |
| Tyr 522 | - | expression tag |
| Lys 523 | - | expression tag |
| Asp 524 | - | expression tag |
| Asp 525 | - | expression tag |
| Asp 526 | - | expression tag |
| Asp 527 | - | expression tag |
| Lys 528 | - | expression tag |
| Gln 362 | Glu 362 | engineered mutation |
| Asp 521 | - | expression tag |
| Tyr 522 | - | expression tag |
| Lys 523 | - | expression tag |
| Asp 524 | - | expression tag |
| Asp 525 | - | expression tag |
| Asp 526 | - | expression tag |
| Asp 527 | - | expression tag |
| Lys 528 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 273773.3 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 1164.5 | |
| All* | Total formula weight | 274937.8 |
