3AVR
Catalytic fragment of UTX/KDM6A bound with histone H3K27me3 peptide, N-oxyalylglycine, and Ni(II)
Summary for 3AVR
Entry DOI | 10.2210/pdb3avr/pdb |
Related | 3AVS |
Descriptor | Lysine-specific demethylase 6A, Histone H3, N-OXALYLGLYCINE, ... (8 entities in total) |
Functional Keywords | cupin superfamily, tri/dimethyllysine demethylase, oxidoreductase-structural protein complex, oxidoreductase/structural protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus (Probable): O15550 |
Total number of polymer chains | 2 |
Total formula weight | 63478.89 |
Authors | Sengoku, T.,Yokoyama, S. (deposition date: 2011-03-07, release date: 2011-10-19, Last modification date: 2023-11-01) |
Primary citation | Sengoku, T.,Yokoyama, S. Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A Genes Dev., 25:2266-2277, 2011 Cited by PubMed: 22002947DOI: 10.1101/gad.172296.111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.803 Å) |
Structure validation
Download full validation report