3AVE

Crystal Structure of the Fucosylated Fc Fragment from Human Immunoglobulin G1

Replaces:  2DTQ

Summary for 3AVE

• Entry DOI: 10.2210/pdb3ave/pdb
• Related: 1E4K 1H3X 1HZH 1L6X 1T83 2DTS 3D6G
• Descriptor: Ig gamma-1 chain C region, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (4 entities in total)
• Functional Keywords: immunoglobulin, igg1, immune system, immunoglobulin-like beta-sandwich
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P01857
• Total number of polymer chains: 2
• Total formula weight: 53186.97

Authors

Matsumiya, S.,Yamaguchi, Y.,Saito, J.,Nagano, M.,Sasakawa, H.,Otaki, S.,Satoh, M.,Shitara, K.,Kato, K. (deposition date: 2011-03-04, release date: 2011-04-06, Last modification date: 2024-10-30)

• Primary citation: Matsumiya, S.,Yamaguchi, Y.,Saito, J.,Nagano, M.,Sasakawa, H.,Otaki, S.,Satoh, M.,Shitara, K.,Kato, K.; Corrigendum to "Structural Comparison of Fucosylated and Nonfucosylated Fc Fragments of Human Immunoglobulin G1" [J. Mol. Biol. 386/3 (2007) 767-779]; J.Mol.Biol., 408:1001-1001, 2011; DOI: 10.1016/j.jmb.2011.03.031

Experimental method

X-RAY DIFFRACTION (2 Å)