3AB4

Crystal structure of feedback inhibition resistant mutant of aspartate kinase from Corynebacterium glutamicum in complex with lysine and threonine

3AB4 の概要

• エントリーDOI: 10.2210/pdb3ab4/pdb
• 関連するPDBエントリー: 2DTJ 3AAW 3AB2
• 分子名称: Aspartokinase, THREONINE, LYSINE, ... (5 entities in total)
• 機能のキーワード: aspartate kinase, concerted inhibition, alternative initiation, amino-acid biosynthesis, atp-binding, diaminopimelate biosynthesis, kinase, lysine biosynthesis, nucleotide-binding, transferase
• 由来する生物種: Corynebacterium glutamicum (Brevibacterium flavum); 詳細
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 517364.02

構造登録者

Yoshida, A.,Tomita, T.,Kuzuyama, T.,Nishiyama, M. (登録日: 2009-11-30, 公開日: 2010-06-23, 最終更新日: 2023-11-01)

• 主引用文献: Yoshida, A.,Tomita, T.,Kuzuyama, T.,Nishiyama, M.; Mechanism of concerted inhibition of {alpha}2{beta}2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum; J.Biol.Chem., 285:27477-27486, 2010; PubMed: 20573952; DOI: 10.1074/jbc.M110.111153

実験手法

X-RAY DIFFRACTION (2.47 Å)