3VK7

Crystal structure of DNA-glycosylase bound to DNA containing 5-Hydroxyuracil

Summary for 3VK7

• Entry DOI: 10.2210/pdb3vk7/pdb
• Related: 3A46 3VK8
• Descriptor: Probable formamidopyrimidine-DNA glycosylase, DNA (5'-D(*GP*TP*AP*GP*AP*CP*GP*TP*GP*GP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*CP*CP*AP*(OHU)P*GP*TP*CP*TP*AP*C)-3'), ... (5 entities in total)
• Functional Keywords: dna glycosylase, hneil1 ortholog, dna lesion, 5-hydroxyuracil, zincless finger, dna binding, hydrolase-dna complex, hydrolase/dna
• Biological source: Acanthamoeba polyphaga mimivirus (APMV)
• Total number of polymer chains: 6
• Total formula weight: 85177.12

Authors

Imamura, K.,Averill, A.,Wallace, S.S.,Doublie, S. (deposition date: 2011-11-10, release date: 2011-12-14, Last modification date: 2023-11-08)

• Primary citation: Imamura, K.,Averill, A.,Wallace, S.S.,Doublie, S.; Structural characterization of viral ortholog of human DNA glycosylase NEIL1 bound to thymine glycol or 5-hydroxyuracil-containing DNA; J.Biol.Chem., 287:4288-4298, 2012; PubMed: 22170059; DOI: 10.1074/jbc.M111.315309

Experimental method

X-RAY DIFFRACTION (2.1 Å)