3VK7

Crystal structure of DNA-glycosylase bound to DNA containing 5-Hydroxyuracil

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Probable formamidopyrimidine-DNA glycosylase	polymer	295	34581.4	2	UniProt (Q5UQ00) Pfam (PF01149) Pfam (PF06831) Pfam (PF21025)	Acanthamoeba polyphaga mimivirus (APMV)	Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase, AP lyase
2	C, E (C, E)	DNA (5'-D(*GP*TP*AP*GP*AP*CP*GP*TP*GP*GP*AP*CP*G)-3')	polymer	13	4056.6	2
3	D, F (D, F)	DNA (5'-D(*CP*GP*TP*CP*CP*AP*(OHU)P*GP*TP*CP*TP*AP*C)-3')	polymer	13	3904.5	2
4	G, H (B, D)	FORMIC ACID	non-polymer		46.0	2	Chemie (FMT)
5	I, J, K, L, M... (A, B, C, D, E...)	water	water		18.0	456	Chemie (HOH)

Sequence modifications

A, B: 1 - 287 (UniProt: Q5UQ00)

PDB	External Database	Details
Gln 3	Glu 3	engineered mutation
Leu 288	-	expression tag
Glu 289	-	expression tag
His 290	-	expression tag
His 291	-	expression tag
His 292	-	expression tag
His 293	-	expression tag
His 294	-	expression tag
His 295	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	85085.1
Non-Polymers*	Number of molecules	2
	Total formula weight	92.0
All*	Total formula weight	85177.1

*Water molecules are not included.