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3UPF

Crystal structure of murine norovirus RNA-dependent RNA polymerase bound to NF023

Summary for 3UPF
Entry DOI10.2210/pdb3upf/pdb
Related3NAH 3NAI 3UQS 3UR0
DescriptorRNA-dependent RNA polymerase, 8-({3-[({3-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)amino]benzoyl}amino)naphthalene-1,3,5-trisulfonic acid, SULFATE ION, ... (4 entities in total)
Functional Keywordsmurine norovirus, rna-dependent rna polymerase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceMurine norovirus 1
Total number of polymer chains3
Total formula weight182372.61
Authors
Milani, M.,Mastrangelo, E.,Bolognesi, M. (deposition date: 2011-11-18, release date: 2012-05-02, Last modification date: 2024-02-28)
Primary citationMastrangelo, E.,Pezzullo, M.,Tarantino, D.,Petazzi, R.,Germani, F.,Kramer, D.,Robel, I.,Rohayem, J.,Bolognesi, M.,Milani, M.
Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases.
J.Mol.Biol., 419:198-210, 2012
Cited by
PubMed: 22446684
DOI: 10.1016/j.jmb.2012.03.008
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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