3UPF

Crystal structure of murine norovirus RNA-dependent RNA polymerase bound to NF023

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	RNA-dependent RNA polymerase	polymer	525	59535.7	3	UniProt (Q80J95) Pfam (PF00680)	Murine norovirus 1
2	D, F, I (A, B, C)	8-({3-[({3-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)amino]benzoyl}amino)naphthalene-1,3,5-trisulfonic acid	non-polymer		1031.0	3	Chemie (0BU)
3	E, G, H, J, K... (A, B, C)	SULFATE ION	non-polymer		96.1	7	Chemie (SO4)
4	N, O, P (A, B, C)	water	water		18.0	625	Chemie (HOH)

Sequence modifications

A, B, C: -6 - 507 (UniProt: Q80J95)

PDB	External Database	Details
Met -9	-	expression tag
Lys -8	-	expression tag
Ala -7	-	expression tag
Leu 508	-	expression tag
Glu 509	-	expression tag
His 510	-	expression tag
His 511	-	expression tag
His 512	-	expression tag
His 513	-	expression tag
His 514	-	expression tag
His 515	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	178607.2
Non-Polymers*	Number of molecules	10
	Total formula weight	3765.4
All*	Total formula weight	182372.6

*Water molecules are not included.