3TUH
Crystal Structure of the N-terminal domain of an HSP90 in the presence of an the inhibitor ganetespib
Summary for 3TUH
Entry DOI | 10.2210/pdb3tuh/pdb |
Descriptor | Heat shock protein HSP 90-alpha, 5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(1-methyl-1H-indol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one (3 entities in total) |
Functional Keywords | chaperone protein, atp binding, chaperone-inhibitor complex, chaperone/inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : P07900 |
Total number of polymer chains | 2 |
Total formula weight | 47513.83 |
Authors | Ying, W. (deposition date: 2011-09-16, release date: 2012-09-19, Last modification date: 2024-02-28) |
Primary citation | Ying, W. Crystal Structure of the N-terminal domain of an HSP90 in the presence of an the inhibitor ganetespib TO BE PUBLISHED, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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