3TDJ
Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and BPAM-97 at 1.95 A resolution
Summary for 3TDJ
Entry DOI | 10.2210/pdb3tdj/pdb |
Related | 1LB9 1LBB 1LBC 3H6T 3IL1 |
Descriptor | Glutamate receptor 2, GLUTAMIC ACID, SULFATE ION, ... (7 entities in total) |
Functional Keywords | ampa receptor ligand-binding domain, glua2 s1s2j-l483y-n754s, bpam-97, allosteric modulation, membrane protein |
Biological source | Rattus norvegicus (rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 2 |
Total formula weight | 60722.62 |
Authors | Krintel, C.,Frydenvang, K.,Gajhede, M.,Kastrup, J.S. (deposition date: 2011-08-11, release date: 2011-09-21, Last modification date: 2023-09-13) |
Primary citation | Krintel, C.,Frydenvang, K.,Olsen, L.,Kristensen, M.T.,de Barrios, O.,Naur, P.,Francotte, P.,Pirotte, B.,Gajhede, M.,Kastrup, J.S. Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2. Biochem.J., 441:173-178, 2012 Cited by PubMed: 21895609DOI: 10.1042/BJ20111221 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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