3T5G
Structure of fully modified farnesylated Rheb in complex with PDE6D
Summary for 3T5G
Entry DOI | 10.2210/pdb3t5g/pdb |
Related | 3T5I |
Descriptor | GTP-binding protein Rheb, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | immunoglobulin-like beta sandwitch, pde delta, rheb, farnesyl, signaling protein, lipid binding protein |
Biological source | Homo sapiens (human) More |
Cellular location | Endomembrane system ; Lipid-anchor ; Cytoplasmic side : Q15382 Cytoplasm, cytosol : O43924 |
Total number of polymer chains | 2 |
Total formula weight | 38507.13 |
Authors | Ismail, S.A.,Chen, Y.-X.,Wittinghofer, A. (deposition date: 2011-07-27, release date: 2011-10-26, Last modification date: 2023-09-13) |
Primary citation | Ismail, S.A.,Chen, Y.X.,Rusinova, A.,Chandra, A.,Bierbaum, M.,Gremer, L.,Triola, G.,Waldmann, H.,Bastiaens, P.I.,Wittinghofer, A. Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo. Nat.Chem.Biol., 7:942-949, 2011 Cited by PubMed: 22002721DOI: 10.1038/nchembio.686 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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