3SI5
Kinetochore-BUBR1 kinase complex
Summary for 3SI5
Entry DOI | 10.2210/pdb3si5/pdb |
Related | 2I3S 2LAH 2WVI 3E7E 3ESL |
Descriptor | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Protein CASC5 (3 entities in total) |
Functional Keywords | bubr1-blinkin complex, mitotic checkpoint, bubr1, blinkin/knl1, chromosome segregation, cell cycle |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: O60566 Nucleus: Q8NG31 |
Total number of polymer chains | 4 |
Total formula weight | 46471.26 |
Authors | Blundell, T.L.,Chirgadze, D.Y.,Bolanos-Garcia, V.M. (deposition date: 2011-06-17, release date: 2011-10-26, Last modification date: 2023-09-13) |
Primary citation | Bolanos-Garcia, V.M.,Lischetti, T.,Matak-Vinkovic, D.,Cota, E.,Simpson, P.J.,Chirgadze, D.Y.,Spring, D.R.,Robinson, C.V.,Nilsson, J.,Blundell, T.L. Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site. Structure, 19:1691-1700, 2011 Cited by PubMed: 22000412DOI: 10.1016/j.str.2011.09.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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