3SDE

Crystal structure of a paraspeckle-protein heterodimer, PSPC1/NONO

Summary for 3SDE

Entry DOI	10.2210/pdb3sde/pdb
Descriptor	Paraspeckle component 1, Non-POU domain-containing octamer-binding protein, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	rrm, anti parallel right handed coiled-coil, nops, dbhs, rna binding protein, rna binding, long non-coding rna, mrna, paraspeckle, nucleus
Biological source	Homo sapiens (human) More
Cellular location	Nucleus, nucleolus: Q8WXF1 Nucleus: Q15233
Total number of polymer chains	2
Total formula weight	60961.65
Authors	Passon, D.M.,Lee, M.,Bond, C.S. (deposition date: 2011-06-09, release date: 2012-03-14, Last modification date: 2024-02-28)
Primary citation	Passon, D.M.,Lee, M.,Rackham, O.,Stanley, W.A.,Sadowska, A.,Filipovska, A.,Fox, A.H.,Bond, C.S. Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation. Proc.Natl.Acad.Sci.USA, 109:4846-4850, 2012 Cited by PubMed: 22416126 DOI: 10.1073/pnas.1120792109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation