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3SDE

Crystal structure of a paraspeckle-protein heterodimer, PSPC1/NONO

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0003723molecular_functionRNA binding
B0003676molecular_functionnucleic acid binding
B0003723molecular_functionRNA binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 1
ChainResidue
AGLN174
AHOH367
BGLU238
BARG251

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 2
ChainResidue
AASN162
ATHR196
AGLY197
ALYS198

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 3
ChainResidue
APRO207
APRO208
AHOH352
AHOH496
AALA205

site_idAC4
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO A 9
ChainResidue
AGLY155
AALA157
ALEU158

site_idAC5
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO A 11
ChainResidue
AHIS315
AGLN316

site_idAC6
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO B 4
ChainResidue
BLEU274
BHOH411

site_idAC7
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO B 5
ChainResidue
BPHE143
BCYS145

site_idAC8
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO B 7
ChainResidue
BPHE171
BGLY172
BGLN173
BALA200
BLYS295

site_idAC9
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO B 8
ChainResidue
BLYS290
BARG293
BHOH399

site_idBC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO B 10
ChainResidue
AHOH339
BGLU128
BASP130
BMET132
BPRO133

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231
ChainResidueDetails
BSER147

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861
ChainResidueDetails
BLYS198

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
BSER262

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q99K48
ChainResidueDetails
BLYS295

site_idSWS_FT_FI5
Number of Residues8
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
BLYS60
BLYS96
BLYS99
BLYS126
BLYS190
BLYS243
BLYS249

site_idSWS_FT_FI6
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733
ChainResidueDetails
BLYS198

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PDB entries from 2024-11-06

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