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3SDE

Crystal structure of a paraspeckle-protein heterodimer, PSPC1/NONO

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Paraspeckle component 1polymer26130000.21UniProt (Q8WXF1)
Pfam (PF00076)
Pfam (PF08075)
Homo sapiens (human)Paraspeckle protein 1
2B
(B)
Non-POU domain-containing octamer-binding proteinpolymer26130278.71UniProt (Q15233)
Pfam (PF00076)
Pfam (PF08075)
Homo sapiens (human)NonO protein, 54 kDa nuclear RNA- and DNA-binding protein, 55 kDa nuclear protein, DNA-binding p52/p100 complex, 52 kDa subunit, NMT55, p54(nrb), p54nrb
3C, D, E, F, G...
(A, B)
1,2-ETHANEDIOLnon-polymer62.111Chemie (EDO)
4N, O
(A, B)
waterwater18.0437Chemie (HOH)
Sequence modifications
A: 61 - 320 (UniProt: Q8WXF1)
PDBExternal DatabaseDetails
Gly 60-expression tag
B: 53 - 312 (UniProt: Q15233)
PDBExternal DatabaseDetails
Met 52-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight60278.9
Non-Polymers*Number of molecules11
Total formula weight682.7
All*Total formula weight60961.6
*Water molecules are not included.

227111

PDB entries from 2024-11-06

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