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3S7K

Structure of thrombin mutant Y225P in the E form

Summary for 3S7K
Entry DOI10.2210/pdb3s7k/pdb
Related1shh 3S7H
DescriptorProthrombin, POTASSIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
Functional Keywordsserine protease, hydrolase
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted, extracellular space: P00734 P00734
Total number of polymer chains4
Total formula weight67741.66
Authors
Niu, W.,Chen, Z.,Gandhi, P.,Vogt, A.,Pozzi, N.,Pele, L.A.,Zapata, F.,Di Cera, E. (deposition date: 2011-05-26, release date: 2011-07-06, Last modification date: 2023-09-13)
Primary citationNiu, W.,Chen, Z.,Gandhi, P.S.,Vogt, A.D.,Pozzi, N.,Pelc, L.A.,Zapata, F.,Di Cera, E.
Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like Protease.
Biochemistry, 50:6301-6307, 2011
Cited by
PubMed: 21707111
DOI: 10.1021/bi200878c
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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