5XJL
Crystal Structure of the Gemin2-binding domain of SMN, Gemin2 in Complex with SmD1/D2/F/E/G from Human
Replaces: 3S6NSummary for 5XJL
Entry DOI | 10.2210/pdb5xjl/pdb |
Descriptor | Gem-associated protein 2, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, ... (8 entities in total) |
Functional Keywords | splicing |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus, gem: O14893 Q16637 Cytoplasm, cytosol : P62314 P62316 P62304 P62306 P62308 |
Total number of polymer chains | 7 |
Total formula weight | 91589.90 |
Authors | Zhang, R. (deposition date: 2017-05-02, release date: 2018-05-02, Last modification date: 2024-03-27) |
Primary citation | Zhang, R.,So, B.R.,Li, P.,Yong, J.,Glisovic, T.,Wan, L.,Dreyfuss, G. Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly Cell, 146:384-395, 2011 Cited by PubMed: 21816274DOI: 10.1016/j.cell.2011.06.043 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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