3RY6
Complex of fcgammariia (CD32) and the FC of human IGG1
Summary for 3RY6
Entry DOI | 10.2210/pdb3ry6/pdb |
Related | 3RY4 3RY5 |
Descriptor | Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor II-a, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | fc receptor, cd32, immunoglobulin superfamily, high responder polymorphism, human igg1, therapeutic antibody, glycoprotein, immunoglobulin c region, immunoglobulin domain, cell membrane, igg-binding protein, membrane, phosphoprotein, receptor, transmembrane, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 73303.44 |
Authors | Ramsland, P.A.,Farrugia, W.,Scott, A.M.,Hogarth, P.M. (deposition date: 2011-05-11, release date: 2011-08-31, Last modification date: 2023-09-13) |
Primary citation | Ramsland, P.A.,Farrugia, W.,Bradford, T.M.,Sardjono, C.T.,Esparon, S.,Trist, H.M.,Powell, M.S.,Tan, P.S.,Cendron, A.C.,Wines, B.D.,Scott, A.M.,Hogarth, P.M. Structural Basis for Fc{gamma}RIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes. J.Immunol., 187:3208-3217, 2011 Cited by PubMed: 21856937DOI: 10.4049/jimmunol.1101467 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.8 Å) |
Structure validation
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