3RNN

Crystal Structure of iGluR2 Ligand Binding Domain with Symmetric Sulfonamide Containing Potentiator

Summary for 3RNN

Entry DOI	10.2210/pdb3rnn/pdb
Related	1FTJ 1FTK 1FTL 1LB9 1LBC 3RN8
Descriptor	Glutamate receptor 2, N,N'-(benzene-1,4-diyldiethane-2,1-diyl)dipropane-2-sulfonamide, GLUTAMIC ACID, ... (5 entities in total)
Functional Keywords	iglur2 ligand binding domain, membrane, transport protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	97628.46
Authors	Timm, D.E. (deposition date: 2011-04-22, release date: 2011-05-25, Last modification date: 2019-07-17)
Primary citation	Timm, D.E.,Benveniste, M.,Weeks, A.M.,Nisenbaum, E.S.,Partin, K.M. Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol.Pharmacol., 80:267-280, 2011 Cited by PubMed: 21543522 DOI: 10.1124/mol.110.070243 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation