3POO
human cAMP-dependent protein kinase in complex with an inhibitor
Summary for 3POO
Entry DOI | 10.2210/pdb3poo/pdb |
Related | 3NX8 3OOG 3OVV 3OWP 3OXT 3P0M |
Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, N'-[(E)-(2,4-dihydroxy-6-methylphenyl)methylidene]-2-(3-methoxyphenyl)acetohydrazide, ... (5 entities in total) |
Functional Keywords | atp binding, phosphorylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P17612 |
Total number of polymer chains | 2 |
Total formula weight | 43439.44 |
Authors | Koester, H.,Heine, A.,Klebe, G. (deposition date: 2010-11-23, release date: 2011-11-16, Last modification date: 2023-09-06) |
Primary citation | Koester, H.,Craan, T.,Heine, A.,Klebe, G. fragment based drug design on PKA To be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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