3OXT

Human cAMP-dependent protein kinase in complex with an inhibitor

Summary for 3OXT

• Entry DOI: 10.2210/pdb3oxt/pdb
• Related: 3N47 3NX8 3OOG 3OWP
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, (2S)-2-amino-N'-[(1E)-(2,4-dihydroxy-6-methylphenyl)methylidene]-2-phenylethanehydrazide, ... (4 entities in total)
• Functional Keywords: transferase, phosphorylation
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P17612
• Total number of polymer chains: 2
• Total formula weight: 43334.31

Authors

Koester, H.,Heine, A.,Klebe, G. (deposition date: 2010-09-22, release date: 2011-09-28)

• Primary citation: Koester, H.,Craan, T.,Brass, S.,Heine, A.,Klebe, G.; Fragment based drug design on PKA; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)