3OEF
Crystal structure of Y323F inactive mutant of p38alpha MAP kinase
Summary for 3OEF
Entry DOI | 10.2210/pdb3oef/pdb |
Related | 3OD6 3ODY 3ODZ |
Descriptor | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside (3 entities in total) |
Functional Keywords | map kinase, inactive mutant, tcr mediated activation, kinase fold, kinase, substrates, phosphotases, upstream activators, y323f, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 41911.93 |
Authors | Livnah, O.,Tzarum, N. (deposition date: 2010-08-12, release date: 2011-01-12, Last modification date: 2024-02-21) |
Primary citation | Tzarum, N.,Diskin, R.,Engelberg, D.,Livnah, O. Active mutants of the TCR-mediated p38alpha alternative activation site show changes in the phosphorylation lip and DEF site formation. J.Mol.Biol., 405:1154-1169, 2011 Cited by PubMed: 21146537DOI: 10.1016/j.jmb.2010.11.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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