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3OEF

Crystal structure of Y323F inactive mutant of p38alpha MAP kinase

Summary for 3OEF
Entry DOI10.2210/pdb3oef/pdb
Related3OD6 3ODY 3ODZ
DescriptorMitogen-activated protein kinase 14, octyl beta-D-glucopyranoside (3 entities in total)
Functional Keywordsmap kinase, inactive mutant, tcr mediated activation, kinase fold, kinase, substrates, phosphotases, upstream activators, y323f, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight41911.93
Authors
Livnah, O.,Tzarum, N. (deposition date: 2010-08-12, release date: 2011-01-12, Last modification date: 2024-02-21)
Primary citationTzarum, N.,Diskin, R.,Engelberg, D.,Livnah, O.
Active mutants of the TCR-mediated p38alpha alternative activation site show changes in the phosphorylation lip and DEF site formation.
J.Mol.Biol., 405:1154-1169, 2011
Cited by
PubMed: 21146537
DOI: 10.1016/j.jmb.2010.11.023
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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