3OEF
Crystal structure of Y323F inactive mutant of p38alpha MAP kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | X | Mitogen-activated protein kinase 14 | polymer | 360 | 41327.2 | 1 | UniProt (Q16539) Pfam (PF00069) In PDB | Homo sapiens (human) | MAP kinase 14, MAPK 14, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A |
| 2 | X | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 2 | Chemie (BOG) | |||
| 3 | water | water | 18.0 | 329 | Chemie (HOH) |
Sequence modifications
X: 1 - 360 (UniProt: Q16539)
| PDB | External Database | Details |
|---|---|---|
| Phe 323 | Tyr 323 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41327.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 584.7 | |
| All* | Total formula weight | 41911.9 |
