3NPA
Glycogen phosphorylase complexed with 2,5-dihydroxy-4-(beta-D-glucopyranosyl)-bromo-benzene
Summary for 3NPA
Entry DOI | 10.2210/pdb3npa/pdb |
Related | 3NP7 3NP9 |
Descriptor | Glycogen phosphorylase, muscle form, (1S)-1,5-anhydro-1-(4-bromo-2,5-dihydroxyphenyl)-D-glucitol (3 entities in total) |
Functional Keywords | glycogenolysis, type 2 diabetes, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits) |
Total number of polymer chains | 1 |
Total formula weight | 97870.47 |
Authors | Alexacou, K.-M. (deposition date: 2010-06-28, release date: 2011-06-08, Last modification date: 2023-11-22) |
Primary citation | Alexacou, K.M.,Zhang, Y.Z.,Praly, J.P.,Zographos, S.E.,Chrysina, E.D.,Oikonomakos, N.G.,Leonidas, D.D. Halogen-substituted (C-beta-D-glucopyranosyl)-hydroquinone regioisomers: synthesis, enzymatic evaluation and their binding to glycogen phosphorylase. Bioorg.Med.Chem., 19:5125-5136, 2011 Cited by PubMed: 21821421DOI: 10.1016/j.bmc.2011.07.024 PDB entries with the same primary citation |
Experimental method |
Structure validation
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